hEPO mRNA encodes human erythropoietin (EPO) that stimulates red blood cell production
hEPO mRNA encodes human erythropoietin (EPO), a 193-amino acid glycoprotein hormone that stimulates red blood cell production (erythropoiesis). The mRNA includes the native N-terminal signal peptide, enabling secretion of the mature EPO protein from transfected cells. EPO mRNA is a widely used benchmark molecule in mRNA therapeutics research for evaluating lipid nanoparticle (LNP) delivery systems, as secreted EPO protein is easily quantified by ELISA in cell culture supernatants and serum.
Note: The human EPO coding sequence (NCBI Gene ID: 2056, UniProt: P01588) is a naturally occurring human gene. This sequence is provided for research use only and is not intended for diagnostic or therapeutic applications without appropriate regulatory approvals.
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